Quillin (32-0-1, 23 KO) pounded Zerafa (17-2, 9 KO) four times in the head during the fifth round before delivering a powerful right-handed knockout blow to Zerafa.
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The blow forced Zerafa to a medical stretcher outside the ring. He was given oxygen but the ringside physician told NBC Sports he would be OK.
Watch as Quillin landed the quivering punch.
Zerafa was taken to local hospital for further evaluations.
This story will be updated.